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Medical case narrative

A young boy, vitamin D, and the difference between a case and a claim

What happened

A boy of 32 months with autism had a vitamin D level of 31.3 nmol/L — deficient. On supplementation, his level rose to 203 nmol/L, and his measured scores improved: the ABC scale fell from 80 to 39, and CARS from 35 to 28.

What it looked like

A developmentally delayed toddler with a genuine, measurable deficiency.

What the labs found

Vitamin D deficiency — real, and worth treating on its own terms.

What changed — and what didn't get proven

His scores improved alongside repletion, and two review papers have re-reported this case. But both reviews retell one uncontrolled case, and a 2017 randomized controlled trial of vitamin D in autism (Kerley) found no effect. This entry is here as a contributor story at its honest weight: correct a deficiency because it is a deficiency, and let controlled trials decide the bigger claims.

The test that told the story

25-hydroxyvitamin D.

Sources: Original case as re-reported in two reviews; Kerley 2017 RCT as counterweight.