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Medical case narrative

A 28-year-old woman — Addison's disease wearing a psychiatric mask

What happened

A 28-year-old woman presented with psychiatric symptoms that were eventually traced to Addison's disease — adrenal failure, in which the body cannot make enough cortisol.

What it looked like

A psychiatric presentation in a young woman, in a condition whose early signs are famously easy to file under stress or depression.

What the labs found

Adrenal insufficiency on hormonal testing, with a markedly elevated ACTH. One caution: the paper prints the ACTH unit as "pmol/mL," which appears to be a typographical unit error — this entry relies on the diagnosis and the pattern, not on quoting that unit.

What changed

A hormone diagnosis with life-sustaining replacement treatment, found because someone tested the endocrine system behind the psychiatric picture.

The test that told the story

Morning cortisol and ACTH (adrenal function testing).

Sources: Published case report.